The archaeological site of Misa, discovered in the town of Marzabotto, is considered to have been an Etruscan outpost. Etruscans settlers coming from the nearby town of Felsina, as Bologna was then called, seeking the richest and most strategic areas of the Bolognese Apennines for their colonies, found this to be a prime location.
The archaeological site of the Reno River Valley includes an ancient Etruscan city in grid formation, flanked by a necropolis whose remains are conserved inside the "P. Aria" National Museum, adjacent the archaeological site and open to the public all year.